raman analyser

Visum Raman In-Line™ - Raman analyser

Industrial analyser based on Raman spectroscopy for in-line and real-time process control.

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PROCESS RAMAN ANALYSER FOR REAL-TIME MONITORING

The Visum In-Line™ Raman analyser is a powerful analytical tool that provides quantitative and qualitative information on a wide variety of substances and mixtures in just seconds, especially suitable for aqueous media (water abundance), in the absence of fluorescence.

TURNKEY SOLUTIONS

In-line Raman spectroscopy is a non-destructive industrial process monitoring technique that requires no sample preparation and inspects by means of a 785nm laser excitation source and a dedicated optical probe the product flow (liquids, powders and solids). It integrates with different working geometries: pipes, tanks and machinery. Visum Raman In-Line™ operates as a fully autonomous and fully integrated process Raman analyser, i.e. it does not require a computer or other external components and communicates directly with the line PLC and plant information system. Visum Raman In-Line™ is a process analytical technology (PAT) tool for the pharmaceutical, biopharmaceutical, plastics, chemical and other industries that allows continuous and safe control, reducing design or manufacturing costs, quality control and time to market. It integrates with process machinery and plant information systems. Raman spectroscopy - unlike NIR spectroscopy - is particularly suitable for aqueous and relatively homogeneous media as well as for the characterization of mixtures involving inorganic compounds. It is therefore a complementary tool to NIR spectroscopy.

Raman Spectroscopy in-line analyzer

Main Features

  • Fully integrated analyser (no external computer required).
  • Connection to the PLC of the line.
  • Its use does not require qualified personnel.
  • Allows analysis of the chemical composition of liquids, powders and solids.
  • Traceability of all measurements.
  • Turnkey supply.

Sectors

Pharma

  • Real-time quantification of APIs and excipients.
  • Quantification of ethanol in complex aqueous matrices.
  • Quantification of CPC (Cetylpyridinium Chloride) in aqueous media.
  • Quantification of Rapamycin in EtOAc (ethyl acetate).
  • Characterisation of reactions.
  • Monitoring of crystallisation processes.
  • Quantifying chemical composition in aqueous media.

Other industries

Show Raman analyser specifications: Hide Raman analyser specifications:

SENSOR

CCD linear array

SENSOR TE COOLING

-40 ºC at ambient temperature of 25 ºC

SPECTRAL RANGE

150 to 3000 cm-1

SPECTRUM ACQUISITION TIME

8ms to 300s (depending on the application)

SPECTRAL RESOLUTION

0.7 nm (11 cm-1)

LASER EXCITATION SOURCE

785 nm

LASER POWER

500 mW

LASER CLASS

4

LASER SOURCE LIFETIME

28k hour MTTF >3years working 24/7

LASER SOURCE WARM-UP TIME

<5 min.

WEIGHT

<10 kg (weight analyser)

DIMENSIONS

400 x 490 x 160 mm3 (without probe)

INGRESS PROTECTION

IP68 (probe) / IP65 (system)

MATERIAL (ENCLOSURE)

AISI 304

POWER SUPPLY

24 VDC

PROCESS OPERATING TEMPERATURE

0 to 250 degC

AMBIENT TEMPERATURE

0 to 40 degC

STANDARD CONNECTION TO THE PROCESS

Immersion probe through a 1/2" BSP Threaded adapter / Triclamp DN64 / Varinline® ( DN68)

CLEAN–IN PLACE

Depending on application

PROBE PROCESS OPERATING PRESSURE

<20 bar.

PROBE IMMERSION DEPTH

up to 100 mm.

MATERIALS (INTERFACE WITH THE PROCESS)

Sapphire window and AISI 316L steel

EMBEDDED COMPUTER

Quad-core ARMv8®

USER INTERFACE

Built-in 10" touch-Screen (control cabinet) or remote connection.

CONNECTIVITY

Modbus TCP / Profibus / OPC-UA / Ethernet / Wi-Fi

SOFTWARE

VISUM®